Genome Analysis

Section-A Basic structure of prokaryotic and eukaryotic genome. Chromatin model, concept of gene, linkage and crossing over, linkage analysis in Drosophilla and Neurospora.
Section-B Pedigree analysis in human genetic mapping and its tools, genetic mapping of complex character. Multigene families in human genome and repetitive DNA C-Value paradox and complexity of genome.
Section-C Physical map of genome Chromosome Walking and Chromosome painting FISH, GISH, Zoo Blot, Dot Blot, VNTR, RFLP‟s RAPD, RACE, SNP‟s, OTL‟s, EST, CPG island identification, Exon trapping and sequence analysis
Rice genome project and its applicability. Human Genome project and its application to future of mankind.

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